Scientific American: “A patient who damaged his left insula, a region of the brain located deep within the cortex on either lateral side, may have opened the door to kick the habit without even trying. The day after suffering a stroke the 38-year-old man, who had a 40-cigarette-a-day addiction, reported to doctors that his ‘body forgot the urge to smoke.’ This revelation prompted a study that found the insula is intimately linked to smoking addiction.”